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Showing posts from January, 2026

In Honor of Otto Jírovec

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If I could talk to Otto (if you don´t know who Otto Jírovec is, but you know Taylor Swift ... stay calm and keep reading. Old school), I’d start by telling him that a lot of things have changed since his days of describing that “interesting rare pneumonia in children” back in the 1930s. I’d mention the internet, AI, the Human Genome Project… and of course, Instagram. But then I’d have questions — serious ones . How is it possible that 40+ years later, with all our technology, Pneumocystis jirovecii is still unculturable? Yes, Otto, we named a bug after you. And second surprise: it’s a fungus. And to be fair, it’s a weird fungus — no ergosterol, lots of glucans. Then I’d explain that today we have four treatment options: ( SPOILER ALERT: not antifungals ) TMP-SMX (oral or IV) — Gold standard  Atovaquone - an inhibitor of mitochondrial Complex III Clindamycin + primaquine Pentamidine - a.k.a. Thanos  [ No Otto,  I wont even try to explain that ] Oh, I al...

Deux ex machina

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I will be honest: I did not know what to write about, but as a “miracle,” this letter arrived at my house. Dr. Jonathan, My name is Arthur, and I do not agree with the superstition called “educational research.” I should clarify this early, because many people could get confused. This is not dysfunction; it is refinement. I work as an editor in a newspaper and as a writer, but I do not write every day. In fact, I let the pressure accumulate. I allow the anxiety to ferment. And when the deadline is close enough to threaten my dignity, I sit down and produce something disturbingly good. According to educational research—which I skimmed a few minutes before writing this to you—this behavior is considered “poor self-regulation.” Apparently, functional adults are supposed to distribute effort evenly, structure their environment, evaluate themselves calmly, and reward small progress. Isn’t this adorable? The same literature claims that excessive self-evaluation without healthy self-cons...

Make America Healthy Again

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For decades, nutrition education was built like a pyramid: solid, hierarchical, and reassuring. Eat this first, limit that, count these nutrients, and health will follow. It was elegant, stable, and very Egyptian. The USDA 2025–2030 Dietary Guidelines draft quietly flips this structure upside down . Instead of placing nutrients at the base, it places context there: culture, access, time, behavior, and the food environment. Nutrients are still important, but they no longer hold the structure. The old model assumed people eat rationally, have access to ideal foods, and follow rules consistently. Clinicians know better. Patients eat under stress, within cultural traditions, and inside systems that often work against healthy choices. We now have not only an inverted—unsteady—pyramid, but one that is carb-shamed, pro-dairy, and productivity protein-driven . Bread, rice, grains: the fuel of civilizations. Then obesity and diabetes rates climbed, and we needed someone to blame. Carbs were con...